COVID-19 Policy Arguments


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Masks

N95 masks are designed for contaminated environments. When one exhales through N95 masks one’s breath is not filtered. Therefore, N95 masks do not prevent infection of others.
Response 1

This applies only to N95 respirators with valves, which are designed for construction/factory workers or miners. However, N95 masks without valves exist and are used by hospitals. Some municipalities have even banned masks with valves for this reason. See link.

Surgical masks are designed for sterile environments. Outdoor contaminants will clog these masks quickly. The moisture from one’s breath combined with the clogged mask will trap SARS-CoV-2 virus particles and lead to becoming a “walking virus dispenser”.
Response 1

Mechanistic studies find that surgical masks could prevent transmission by infected persons. See links (1, 2)

Response 1

A meta-analysis of 10 randomized controlled trials finds that surgical mask use within a community does not lead to any significant reduction in influenza transmission, although this does not show that surgical masks are harmful. See link.

Response 1

The authors of that study pointed out significant limitations: small sample size and suboptimal adherence in the mask-wearer group.

Response 2

Even if surgical masks could potentially have no benefit, if the weight of the evidence shows that they either have no benefit or prevent transmission, it would be better to wear surgical masks than not because there is little cost to doing so.

Cloth masks do not filter one’s breath and therefore provide no benefit with respect to COVID-19 transmission.
Response 1

Cloth masks can act as a physical barrier to prevent large droplets from passing through. See link.

Response 2

A study finds that homemade cloth masks, although less effective than surgical masks, still significantly reduce the number of microorganisms expelled by wearers. See link.

Response 3

Even if cloth masks could potentially have no benefit, as long as they are not an active harm it would be better to wear cloth masks than not because there is little cost to doing so.

Cloth masks are dangerous because they can trap carbon dioxide and cause wearers to breathe in excessive carbon dioxide. Furthermore, studies exist which show that masks can have an effect on breathing. See link.
Response 1

Although masks can have an effect, it is not sufficient to endanger one’s health; it will be relevant only when going through strenuous physical activity, such as exercising. See link.

Lockdowns

Lockdowns were too initially strict or too lengthy, which led to lower compliance with policies later on.
The largest bottleneck to ending lockdowns, prior to the successful development of vaccines, was the number of tests performed per day.
Response 1

Testing alone cannot successfully end lockdowns, because missing even a small number of people with mass testing will allow the pandemic to start again once the lockdowns are lifted. Furthermore, any appreciable false negative or false positive rate will make this problem even worse.

Response 1

This is not a binary scenario. It would be better to miss only a small number of people than millions with testing.

Lockdown policies should be removed for individuals who have obtained the vaccine. This is because the largest incentive for vaccination is the potential to return to a regular lifestyle, and if this is not possible (or perceived not to be possible) then people, especially those hardest to reach with institutional messaging, will be much less likely to become vaccinated.
Response 1

The goal of the CDC and many such similar institutions is not to give the most practical advice, but rather the most health conscious. For example, the CDC recommends or has recommended that steaks always be cooked to at least medium, that women who are not on the pill should never consume alcohol because they may be pregnant, and so on. As such, it is completely appropriate for the CDC to indicate that the safest course of action is to continue with e.g. social distancing even when vaccinated, even if practically speaking it would be generally appropriate for some given individual to do otherwise.

Response 2

It is impractical to do this because people who have been vaccinated cannot be easily distinguished from people who have not been.

Many rules during the lockdowns in the United States were inconsistent or foolish. For example, in Michigan stores were banned from selling non-essential items even if they were otherwise permitted to be open (for example, open grocery stores were not allowed to sell gardening supplies).
Response 1

This could be due to issues with fairness. For example, if greenhouses are not considered essential and thus closed, but big grocery stores are allowed to sell the same products, then it would prevent there from being any pent-up demand for those closed greenhouses (thus placing them in even more dire financial straights) and would unduly favor the grocery stores.

Response 1

This goal was not achieved by the lockdown orders because everyone is able to purchase products from online stores such as Amazon.

Many people are unable to make a voluntary decision about whether to remain at their jobs or not because they would be unable to undergo the economic hardship of losing their jobs. Lockdowns can remedy this issue.
Response 1

If this was really the concern, mandatory temporary furlow and basic income for those who must stop working due to health would be more appropriate than lockdown. If there are people who would be worse off without a job than taking the risk of the pandemic, then removing the option of continuing with their job through lockdown does not improve their situation.

Full eradication and control over the pandemic is demonstrably possible as shown by the example of China.
Response 1

Some abnormalities, such as extremely high demand for funeral urns, showed that the pandemic was not under control at the time it was claimed to be.

Response 1

This does not necessarily show extra COVID-19 deaths. Rather, it could simply be pent-up demand from other deaths during the harsh lockdowns.

Response 2

Daily life in China has generally preceded unlike it would have if the pandemic really were raging unabated. See link.

Antibody passports are not a good idea, as they could incentivize people trying to catch the virus. It could potentially spawn a black market in counterfeits. Furthermore, as there are limitations in testing capacity, it could cause disproportionate problems for people with fewer resources.
Response 1

In contrast to the situation where everyone must accept lockdown restrictions, it seems like purely a positive good to allow those with no ability to spread or be infected by the virus to live a regular life.

Response 2

In general, if there are individuals who stand to gain from some intervention, then those individuals should have to pay for that intervention themselves, as is the case with consumer goods.

Response 1

Many individuals are unable to pay for certain interventions themselves, and it is generally accepted that they should be given governmental assistance in cases such as with healthcare, lack of which could potentially pose a threat to their life.

Lockdowns are worth the economic cost because the statistical value of a life lost exceeds the cost to the economy. The total value of lives that would be lost to an unrestricted pandemic (the value of statistical life multiplied by the number of lives lost) would be about $6 trillion, about 30% of annual GDP. See link.
Response 1

The methodology of determining the value of a statistical life is not appropriate here. Here is the methodology: ‘Suppose each person in a sample of 100,000 people were asked how much he or she would be willing to pay for a reduction in their individual risk of dying of 1 in 100,000, or 0.001%, over the next year. Since this reduction in risk would mean that we would expect one fewer death among the sample of 100,000 people over the next year on average, this is sometimes described as "one statistical life saved.” Now suppose that the average response to this hypothetical question was $100. Then the total dollar amount that the group would be willing to pay to save one statistical life in a year would be $100 per person × 100,000 people, or $10 million. This is what is meant by the "value of a statistical life.”’ This has issues because people are firstly unable to comprehend and meaningfully reason about very small probabilities, similarly to very large numbers. Furthermore, this approach does not work because people are naturally less willing to pay for extending other lives rather than their own. Although it is possible to make a moral argument about the equality of people’s lives and other factors, this does not show that an unrestricted pandemic would be more economically costly than with lockdown measures.

Lockdowns are worth the economic cost because the statistical value of a life lost exceeds the cost to the economy. The total value of lives that would be lost to an unrestricted pandemic (the value of statistical life multiplied by the number of lives lost) would be about $6 trillion, about 30% of annual GDP. See link.
Response 1

The methodology of determining the value of a statistical life is not appropriate here. Here is the methodology: ‘Suppose each person in a sample of 100,000 people were asked how much he or she would be willing to pay for a reduction in their individual risk of dying of 1 in 100,000, or 0.001%, over the next year. Since this reduction in risk would mean that we would expect one fewer death among the sample of 100,000 people over the next year on average, this is sometimes described as "one statistical life saved.” Now suppose that the average response to this hypothetical question was $100. Then the total dollar amount that the group would be willing to pay to save one statistical life in a year would be $100 per person × 100,000 people, or $10 million. This is what is meant by the "value of a statistical life.”’ This has issues because people are firstly unable to comprehend and meaningfully reason about very small probabilities, similarly to very large numbers. Furthermore, this approach does not work because people are naturally less willing to pay for extending other lives rather than their own. Although it is possible to make a moral argument about the equality of people’s lives and other factors, this does not show that an unrestricted pandemic would be more economically costly than with lockdown measures.

Lockdowns are worth the economic cost because the statistical value of a life lost exceeds the cost to the economy. The total value of lives that would be lost to an unrestricted pandemic (the value of statistical life multiplied by the number of lives lost) would be about $6 trillion, about 30% of annual GDP. See link.
Response 1

The methodology of determining the value of a statistical life is not appropriate here. Here is the methodology: ‘Suppose each person in a sample of 100,000 people were asked how much he or she would be willing to pay for a reduction in their individual risk of dying of 1 in 100,000, or 0.001%, over the next year. Since this reduction in risk would mean that we would expect one fewer death among the sample of 100,000 people over the next year on average, this is sometimes described as "one statistical life saved.” Now suppose that the average response to this hypothetical question was $100. Then the total dollar amount that the group would be willing to pay to save one statistical life in a year would be $100 per person × 100,000 people, or $10 million. This is what is meant by the "value of a statistical life.”’ This has issues because people are firstly unable to comprehend and meaningfully reason about very small probabilities, similarly to very large numbers. Furthermore, this approach does not work because people are naturally less willing to pay for extending other lives rather than their own. Although it is possible to make a moral argument about the equality of people’s lives and other factors, this does not show that an unrestricted pandemic would be more economically costly than with lockdown measures.

Many aspects of the lockdown measures were unnecessary, such as restricting public parks, as superspreader events have not occurred outdoors. Furthermore, keeping facilities such as parks open provides a sort of pressure valve that could improve compliance with other lockdown policies.
Response 1

It was not necessarily known early on in the pandemic that outdoor events would not result in spikes in cases of COVID-19. Given the uncertainty around the pandemic, it may have been better to be safe than sorry.

Flattening the curve will not necessarily be effective, because once restrictions are relaxed infections will begin to increase again (assuming insufficient immunity). For example, multiple superspreader events occurred in South Korea following relaxation of restrictions.
Response 1

This is no longer relevant due to the successes of vaccine development.

A large percentage of deaths are in nursing homes. For example, in Seattle’s King County, by May of 2020 64% of all deaths were in nursing homes, which would not be affected by lockdown orders regulating the rest of society. See link.
Support of opening up should be in concert with support of wearing masks, because proper mask-wearing eliminates most risks of going out.
Response 1

Although mask-wearing might be appropriate, criminalizing going outside without a mask is not appropriate either due to concerns about civil liberties.

Lockdown restrictions are similar in concept to abstinence-only sex education, which promotes the total elimination of risk (of STDs, unintended pregnancies, etc.). However, these are often ineffective, in part because it deprives people of understanding of how to manage their risk, especially because neither of these are capable of reaching 100% compliance. Instead, harm-reduction policies, such as promoting education on higher-risk and lower-risk activities or even how risks can be reduced in particular settings, would be more appropriate to reduce deaths.
Response 1

Sex is (generally) consensual and does not occur in public. This makes STDs very different from something like COVID-19, with which people can infect one another by merely standing in each other’s vicinity. One cannot be blamed for being infected with COVID-19 if someone at the checkout line of a store came to close, but the same cannot be said of STDs.

Response 1

Sex is (generally) consensual and does not occur in public. This makes STDs very different from something like COVID-19, with which people can infect one another by merely standing in each other’s vicinity. One cannot be blamed for being infected with COVID-19 if someone at the checkout line of a store came to close, but the same cannot be said of STDs.

Response 1

One similarity in both cases is that people’s behaviors are not controllable enough for abstinence-only education (or lockdown mandates) to work. This means that both of these have issues with their effectiveness in achieving their own goals.

Some proposed restrictions, such as requiring some kind of ID in order to patronize restaurants, have similar problems with potential discrimination as do voter ID laws.
Response 1

Voting is a right, while eating is a restaurant is not a right.

Response 1

In the United States, it is not legal in either situation to discriminate on the basis of race, including through many factors that are not race itself if they could result in disparate impact.

Response 2

Voting has very little individual effect and bears very little relevance to the daily lives of anyone. In contrast, people regularly interact with businesses such as restaurants, so potential discrimination in the latter is more impactful.

COVID-19 is no worse than a particularly bad flu season, or at least within the same magnitude.
Response 1

The number of COVID-19 related deaths clearly demonstrates that COVID-19 is much worse than the flu, although not necessarily orders of magnitude worse. See link.

Response 2

About one in one thousand children exposed to COVID-19 are affected by a Kawasaki-like disease. Furthermore, that COVID-19 can cause this is evidence that it could potentially do other forms of serious long-term harm, as “bad things” in terms of poor health are correlated since things that harm you one way are likely to harm you in others.

Response 1

The fact that this was not discovered until relatively late is evidence that these factors cannot be too common or serious. Furthermore, Kawasaki’s seems to result only in 6 excess deaths in a follow-up study of 4595 cases, so the actual death rate caused by approximately 1/1000 of 1/1000 children exposed to COVID-19 seems minute. See link.

The original goal of lockdowns were to flatten the curve so as to prevent hospital systems from being overwhelmed. However, hospital systems generally were not overwhelmed, even in the worst moments of the pandemic. Furthermore, states that loosened restrictions did not see massive outbreaks follow.
Response 1

Although hospital beds were available, there was a shortage of PPE, kidney dialysis machines, etc. Therefore, it is not necessarily accurate to say that there was no danger of hospital systems being overwhelmed.

Response 2

IFRs in the most overwhelmed areas were significantly higher than in areas which were hit less hard. This supports the idea that overwhelmed hospital systems can lead to significantly higher death rates, even if hospital systems were not literally overflowing.

Lockdowns themselves can cause deaths, so measurements of excess deaths cannot be attributed simply to “the pandemic” and therefore cannot be used to support lockdown policies. For example, people in lockdown are less likely to call emergency services, which causes preventable deaths. See link.
Response 1

Lockdowns can also save lives that would have otherwise been lost for non-COVID-19 related reasons, such as reduction in violent crimes, some types of driving accidents, other infectious diseases, and so on.

Response 2

Many of the problems attributed to lockdowns, such as economic contractions, could easily be caused by people choosing on their own to e.g. socially distance and refrain from going out. If most people do not participate in a reopening, then similar problems would occur in any case.

Response 3

In Italy, a nationwide lockdown was implemented on March 9th. This graph shows the relationship between reported cases per 100,000 people and excess deaths per 100,000 people within each Italian province. The data is from April 15th, and excess deaths are measured relative to 2015-2019 averages. The 41 least infected provinces (as measured by cases per 100,000 people) combine for zero excess deaths in 2020. These provinces account for 20.9 million of Italy's 60.4 million population. This offers suggestive evidence that lockdowns have very little effect on non-COVID mortality in the short-run.

Response 1

This may be confounded by various factors. For example, lockdowns can prevent deaths due to causes such as drunk driving, but this is not related to COVID-19. Lockdowns could also be more stringently enforced in areas where the pandemic is more serious.

Response 2

A 2011 meta-analysis of studies examining unemployment and all-cause mortality find a hazard ratio of unemployment to baseline of 1.63. The naive calculation of multiplying the average working-age yearly mortality of about 0.2% by 1.63 for 1% of the 160 million US workforce gives about 2,000 yearly deaths. Therefore, even a huge drop in employment (which, in this circumstance, would be much less bad than usual given the large increases to unemployment insurance and COVID-19 checks) would be less than the deaths caused directly by COVID-19.

Response 1

This analysis does not take into account quality of life or the quantity of life-years actually saved. For example, health insurance decisions are often made by comparing quality-adjusted life years rather than raw years of living or just “deaths”; saving the lives of elders already close to death may not be equivalent to saving one working-age person, from a utilitarian standpoint.

There were relatively few deaths in the United States that resulted from the pandemic – much fewer than other causes of death, such as heart attacks. Therefore, the measures taken to address the pandemic were an overreaction.
Response 1

The measures were taken to prevent an even worse situation. Therefore, even if it might appear to be an overreaction, as we cannot observe the counterfactual this is not a good method to evaluate lockdown policies. If no measures were applied, then it is possible than many more people would have died.

Response 1

“If lockdown measures are working then they’ll look like an overreaction” is also not a good argument in support of lockdowns, as similar evidence would be expected in both cases even assuming the premise is true.

Although lockdowns might appear to be a good idea in theory, in practice they do not affect behavior. For example, CDC graphs using cell phone data to measure the percent of people leaving home over time show that official government stay-at-home orders did not affect the percentage of people staying at home. France and Italy were heavily affected early in the pandemic whereas Germany did fairly well; this effect was replicated in French, Italian and German-speaking Swiss cantons despite the clear difference in governance. Furthermore, Sweden, the Netherlands, and Japan are reputed to have had weak or nonexistant lockdowns but have not done substantially worse than other countries.
Cases rose in states that relaxed precautions, such as Texas and Florida. Therefore, restrictions are an effective method of preventing new COVID-19 cases. See link.
Response 1

States that saw strong, continuous lockdowns such as New York generally had early large outbreaks, which would itself prevent the possibility of future large outbreaks. Therefore, the relationship cannot be identified as causal.

Lockdowns may be causing a severe mental health crisis. This can influence suicide rates in the medium term but also cause long-term mental harm short of that.
Response 1

Data on suicide rates shows that they have actually been lower than usual, or at least not higher. See link.

Response 1

Many single-vehicle accident fatalities and overdose deaths are not ruled as suicides and therefore do not show up in the data, even if they are likely to be suicides. Furthermore, both of these surged during the pandemic. See links (1, 1)

Many instances of relaxed policies, such as allowing in-person voting and protests, have not lead to significant spikes in deaths.
Response 1

This does not account for exponential growth. It could be possible that the relaxation of restrictions leads to additional cases, but this will not be an obvious spike until long in the future.

U.S. states with strong lockdowns also had disproportionate deaths from COVID-19. Therefore, lockdowns do not work.
Response 1

It is easily possible that causality runs the other way: because these states had disproportionate deaths, they applied stronger lockdown policies. Furthermore, these states have greater density and are more urban, which could increase susceptibility to COVID-19.

Response 1

Tokyo is also very dense, has crowded subways, an old population, and so on but did not see significant COVID-19 deaths.

Response 1

Tokyo still saw a disproportionate share of deaths within Japan. Therefore, while the Japanese context may be a confounder, density still appears to increase susceptibility to COVID-19.

Elected officials and governments stand to gain from implementations of the lockdown, as they will refuse to relinquish their new powers in the future.
Response 1

Elected officials have not benefited from the crisis, as it has distracted them from other goals that they might prefer to prioritize. Furthermore, lockdown policies have alienated parts of the electorate, which is undesirable for elected officials.

Response 1

Crises and wars allow governments to radically realign society, everyday life, or at the very least the government itself in order to combat the crisis. For example, both world wars lead to vast changes in society on the home front, many implemented by countries’ respective governments. Another example might be stagflation, which lead to the election of Reagan and realignment against the Keynesian economic orthodoxy of the time.

Response 2

Lockdowns have been tailored according to the preference of policymakers, which can often be arbitrary and even politically motivated. For example, Massachusetts Governor Charlie Baker initially allowed gun retailers to remain open with social distancing measures in his initial lockdown order, but soon altered the order to prohibit gun stores from being open in any capacity after being contacted by anti-gun Democrats. See link.

Response 2

State governments that have implemented strong lockdowns have received enormous budgetary losses, so there is little financial incentive for it.

Response 1

Although a country might be poorer, controlling more political power in that country might still be a net gain for an individual in that country. For example, many civil wars lead to economic contractions, but the victor is nonetheless in a more powerful position than before.

Hydroxychloroquine

Hydroxychloroquine has been found ineffective by many studies.
Response 1

Many of those studies have been underpowered or administered hydroxychloroquine too belatedly to be of use. For example, this study shows that hydroxychloroquine reduces risk by about 18% and reduces the risk even more strongly for those who took it earlier. Although it does not reach the 95% significance threshold, a preponderance of non-decisive evidence can still inform individual decisions or even policy.

Response 1

Post-hoc analysis of data in this way amounts to p-hacking and cannot reliably deliver any kind of evidence due to the ease of tailoring that analysis to confirm pre-existing bias.

Response 2

The WHO claims hydroxychloroquine does not increase risk of death for COVID-19 patients, so there is little cost to using it and a potentially large benefit. See link.

Response 3

Although naturally causality cannot be clearly determined, countries that have been using hydroxychloroquine, such as Honduras, saw a significant drop in mortality after implementing the treatment.

Hydroxychloroquine was found to be actively harmful by a study published in The Lancet. However, this study was later found to have used fraudulent data.

Case Statistics

Case statistics are unreliable because the CDC and various states mix data from an antibody and viral tests. The former likely demonstrates whether someone has ever been sick, with some caveats, whereas the latter demonstrates whether or not they are sick at the moment. Mixing statistics from both tests obscures the meaning of positive tests. See link.
Response 1

The CDC only aggregates data provided to them by the states into national statistics and released their interim case definition by early April of 2020. Insofar as states have conflated statistics, they have been violating the CDC guidelines.

“New case” data was unreliable because it was more dependent on the total amount of testing than any real change in the infection rate. This can be seen by comparing the graphs of total tests and positive tests.
It is inappropriate to use regional statistics, such as in Bergamo or in New York, due to various unknowns. Furthermore, policies such as requiring nursing homes to take in COVID-19 positive patients in New York or using beds in homes for the elderly to make up for hospital bed shortages in Lombardy were disastrous, but not replicated in other areas.
The Ferguson model has many issues. For example, the results vary strongly even given identical starting conditions. Furthermore, regardless of how parameters are adjusted, the model badly estimates the total deaths in many countries. See link.
It is difficult to compare test statistics between different jurisdictions because the standards for collection differ. For example, Belgium was considered one of the worst hit countries in early 2020, but it also had very lax standards for COVID-19 death reports. It sufficed to report that a patient had COVID-like symptoms even if they did not die in the hospital and no test was made.

Miscellaneous

Test-and-trace is not a viable solution at scale. The lengthy presymptomatic-but-contagious window would prevent the possibility.
Response 1

While in the U.S. there is insufficient public health infrastructure, in smaller countries with a dedicated apparatus it may be achievable.

Response 1

There is a strong incentive not to be diagnosed with COVID-19 because receiving a positive test could easily create a lot of trouble - for example increasing scrutiny and even closing facilities that have been visited. In Hong Kong, a positive test could even result in separation from one’s children.

Response 2

Singapore is generally considered a competent country that is also very small, but it ultimately gave up on test-and-trace.

“Although it cannot be confirmed that SARS-CoV-2 was “made in a lab”, there was genetic recombination research on coronaviruses being funded by the NIH in both Chapel Hill and Wuhan. This research could potentially explain how the virus, which otherwise seems to have originated in bats, came to incorporate a pangolin spike protein, and was first observed 600 km from the known Yunnan cave origin. See link.
A major reason for the sluggishness of the initial U.S. response was the obstructionism of the FDA against tests. "Precautionary government regulation often undercuts the resilience the system is able to show when confronted with a new peril or emergency."
Response 1

Unregulated tests could easily create either hysteria or false confidence if they are not properly functional, administered by untrained users, or even scams.

Response 1

Cutting corners is a necessary response to an emergency when increasing capacity is more important than 100% accuracy or reliability. Even a potentially faulty test or treatment is better than none at all in a life-or-death situation.

Response 2

The official test had some notable failures. For example, the initial batch sent out by the CDC was contaminated and thus unusable for its function. Therefore, the proposed benefit of regulation did not manifest.

Response 2

Distrust of medical institutions and procedures is a major problem, and removing the regulatory authority of the FDA would exacerbate this issue.

Response 1

The FDA is also one such distrusted institution, so this would not necessarily occur to an appreciable degree. In fact, perceived FDA obstructionism early in the pandemic may have contributed to worsening this problem.

For many people, taking the vaccine would not be in their personal interest. This is because proper vaccine development takes 2-5 years. A rushed vaccine would, therefore, necessarily have heightened risk, although it is possible that it would be the best choice for those vulnerable to COVID-19. Furthermore, in the past, a rushed vaccine in response to a swine flu outbreak had worse effects than the outbreak itself because it triggered Guillain–Barré Syndrome in some users; because COVID-19 is seen as even more pressing, it is likely that this vaccine would be even more rushed and flawed. Finally, because institutional authorities have shown to be flawed on the subject of COVID-19 previously, assurances that the vaccine is safe cannot necessarily be trusted, and personal evaluation would be impractical.
Response 1

If one considers only personal interest, this calculus could easily be changed through policy measures incentivizing vaccination. For example, proposals to condition a "return to normalcy" on evidence of being vaccinated would strongly shift this, especially if the relevant vaccine appears to be generally safe.

Due to the potential of a COVID-19 outbreak among the incarcerated, the release of people imprisoned for petty crimes is appropriate.
Response 1

The incarcerated are effectively in quarantine to begin with and are trivial to relocate within a prison compound.

Response 2

Such policies can lead to other negative effects, such as rises in crime rates or drug use.

Response 1

Anecdotally, cities such as San Francisco which used such policy measures did not have their quality of living unduly effected. There are only a few bad areas, which may be unfortunate for the people who live there, but do not affect most residents.

They may be a pattern of the very old and sick clustering in cities, in the same way younger people and jobs have clustered in cities, because when people are close to death they move to where their children are. Thus, the IFR in cities would be far increased compared to rural areas.
Response 1

Viewing a list of states by median age shows that there is no clear pattern of stereotypically rural states being older or younger than stereotypically urban ones. The top 5 are Maine, New Hampshire, Vermont, West Virginia, and Florida. 4 of these are mostly rural while the remaining one is North America's #1 Retirement Destination. But the bottom is similar - 5 youngest states are Utah, Alaska, Texas, North Dakota, and Nebraska.

Response 1

These arguments are not necessarily incompatible, because it is not necessary for the old and sick to be disproportionately likely to live in the city, but only that they are likely to move closer to cities when near to death.

Research suggests that the Pfizer-BioNTech COVID-19 vaccine "induces complex reprogramming of innate immune responses that should be considered in the development and use of mRNA-based vaccines." See link.
Response 1

This (non-peer-reviewed) study shows only that a small minority of the non-specific antigens they tested cause lymphocytes from people who got the vaccine to respond differently from those of people who did not receive the vaccine. The differences are statistically significant but the magnitude is fairly small. They did not compare it to other vaccines. In short, it is not a surprise that an injection known to cause inflammation (which is desirable so that immune cells are recruited to the site of injection) causes a short-term change in how the body reacts to other things that might also cause inflammation.


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